Understanding The Cell Cyclemr. Mac's Page


EVOLUTION 101

The causes of mutations

Mutations happen for several reasons.

  1. DNA fails to copy accurately
    Most of the mutations that we think matter to evolution are 'naturally-occurring.' For example, when a cell divides, it makes a copy of its DNA — and sometimes the copy is not quite perfect. That small difference from the original DNA sequence is a mutation.


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  2. External influences can create mutations
    Mutations can also be caused by exposure to specific chemicals or radiation. These agents cause the DNA to break down. This is not necessarily unnatural — even in the most isolated and pristine environments, DNA breaks down. Nevertheless, when the cell repairs the DNA, it might not do a perfect job of the repair. So the cell would end up with DNA slightly different than the original DNA and hence, a mutation.


Mechanisms
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Learn more about mutation in context:
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  • A chink in HIV's evolutionary armor, a news brief with discussion questions.


Teach your students about mutation:
  • Origami birds, a classroom activity for grades 9-12.
  • Solving the mystery of the Neanderthals, a web activity for grades 9-12.

Find additional lessons, activities, videos, and articles that focus on mutation.


Understanding The Cell Cyclemr. MacMacCyclemr.Understanding the cell cyclemr. mac

The cell cycle is an ordered series of events involving cell growth and cell division that produces two new daughter cells. Cells on the path to cell division proceed through a series of precisely timed and carefully regulated stages of growth, DNA replication, and division that produces two identical (clone) cells.

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